Special Issue: Gram-Positive Bacterial Toxins

Gram-positive and gram-negative bacterial toxins in sepsis

Bacterial sepsis is a major cause of fatality worldwide. Sepsis is a multi-step process that involves an uncontrolled inflammatory response by the host cells that may result in multi organ failure and death. Both gram-negative and gram-positive bacteria play a major role in causing sepsis. These bacteria produce a range of virulence factors that enable them to escape the immune defenses and dis...

The cholesterol-dependent cytolysin family of gram-positive bacterial toxins.

The cholesterol-dependent cytolysins (CDCs) are a family of beta-barrel pore-forming toxins secreted by Gram-positive bacteria. These toxins are produced as water-soluble monomeric proteins that after binding to the target cell oligomerize on the membrane surface forming a ring-like pre-pore complex, and finally insert a large beta-barrel into the membrane (about 250 A in diameter). Formation o...

Special Issue on Marine Toxins

The special issue on Marine Toxins of the Open Access journal Marine Drugs (ISSN 1660-3397, http://www.mdpi.com/journal/marinedrugs/) presents twenty four contributions which were received from distinguished investigators currently working in Canada, China, France, Germany, Iran, Italy, Japan, Portugal, Russian Federation, Slovenia, South Africa, Spain, and the United States. The reviews and re...

An Introduction to the Toxins Special Issue on “Novel Pharmacological Inhibitors for Bacterial Protein Toxins”

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Introduction to the Toxins Special Issue on Plant Toxins